Video: Question: APP processing and synaptic function.
At the conclusion of the panel discussion, the floor was opened to questions from the audience. In this first question, Hélène Marie (IPMC and CNRS, France) asks whether APP processing (and the various resulting fragments) may play a substantive role in normal, physiological regulation of synaptic function and whether perturbations to this system may then underlie toxicity and synaptic dysfunction which occurs during the early stages of the disease.
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